BSU Seminar: “Using Electronic Health Records for Scientific Research: Promises and Perils”

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• Professor Bhramar Mukherjee, John D. Kalbfleisch Collegiate Professor of Biostatistics, University of Michigan
• Tuesday 22 November 2022, 14:00-15:00
• Large Seminar Room, East Forvie Building, Forvie Site, Robinson Way, Cambridge CB2 0SR.

If you have a question about this talk, please contact Alison Quenault.

This will be a free hybrid seminar. To register to attend virtually, please click here: https://us02web.zoom.us/meeting/register/tZctduyqrjgsEtYxJkz-fTWdzMmjL7qFrnAC

Electronic Health Records (EHR) linked with other auxiliary data sources hold tremendous potential for conducting real time actionable research. However, one has to answer two fundamental questions before conducting inference: “Who is in my study?” and “What is the target population of Inference?”. Without accounting for selection bias, one can quickly produce rapid but inaccurate conclusions. In this talk, I will discuss a statistical framework for jointly considering selection bias and phenotype misclassification in analyzing EHR data. Examples will include genome and phenome-wide association studies of Cancer and COVID -19 outcomes using data from the Michigan Genomics initiative and the UK Biobank. This is joint work with Lars Fritsche, Lauren Beesley and Maxwell Salvatore at the University of Michigan School of Public Health.

This talk is part of the MRC Biostatistics Unit Seminars series.

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