Virtual Seminar: 'Using auxiliary variables in mediation analysis to address unmeasured confounding'

Add to your list(s) Download to your calendar using vCal

• Professor Richard Emsley, NIHR Research Professor, Institute of Psychiatry, Psychology and Neuroscience, King’s College London
• Tuesday 10 November 2020, 14:00-15:00
• Virtual Seminar .

If you have a question about this talk, please contact Alison Quenault.

If you would like to join this virtual seminar, please email: research_admin@mrc-bsu.cam.ac.uk for more information.

Causal mediation analysis aims to estimate natural direct and natural indirect effects under clearly specified assumptions. Traditional mediation analysis based on ordinary least squares (OLS) estimation assumes an absence of unmeasured causes to the putative mediator and outcome, even in randomised studies. When these assumptions cannot be justified, instrumental variables (IV) estimators can be used to produce an asymptotically unbiased estimator of the mediator-outcome link. However, this bias removal comes at the cost of variance inflation and requires additional parametric assumptions about the validity of the instruments. I will describe the statistical approaches for identification and estimation of parametric regression and instrumental variable analyses, including examples of multiple instruments. I will introduce a new estimator that strikes a natural trade-off between the unbiasedness of the IV procedure and the relatively small variance of the OLS estimator.

This talk is part of the MRC Biostatistics Unit Seminars series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• BHRU Annual Lecture 2015
• BHRU Annual Lecture 2016
• Biology
• Cambridge Centre for Data-Driven Discovery (C2D3)
• Cambridge Immunology
• Cambridge talks
• Cardiovascular Epidemiology Unit Special Seminars
• Chris Davis' list
• Department of Public Health and Primary Care
• Graduate-Seminars
• Interested Talks
• Life Sciences
• Life Sciences
• ME Seminar
• MRC Biostatistics Unit Seminars
• Primary Care
• PublicHealth@Cambridge
• Trust & Technology Initiative - interesting events
• Virtual Seminar
• bld31
• my_list
• ndk22's list
• ob366-ai4er
• other talks
• primary care
• rp587

Note that ex-directory lists are not shown.