“Squeezing the most out of ridge”

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• Professor Mark van de Wiel, Amsterdam University Medical Center
• Tuesday 03 March 2020, 14:00-15:00
• Large Seminar Room, 1st Floor, Institute of Public Health, University Forvie Site, Robinson Way, Cambridge.

If you have a question about this talk, please contact Alison Quenault.

Ridge regression is nowadays regarded as a somewhat old-fashioned technique: most statisticians prefer sparse models, while machine learners use non-linear, multi-layer prediction algorithms. The aim of this talk is to endorse ridge by illustrating its strengths, from a methodological, computational and applied perspective, including:

Flexibility (in terms of output and type of covariates)

Bayesian counterpart facilitates empirical Bayes estimation of penalty parameter(s)

Differential penalization for multi-modal (e.g. multi-omics) data

Penalty weights moderated by (external) information on the features:

Co-data

Effective posterior feature selection

Computational efficiency

Performance in clinical (omics) prediction problems

These strengths will be illustrated on a cancer multi-omics prediction problem.

This talk is part of the MRC Biostatistics Unit Seminars series.

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