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Stem Cell Ageing: Reversing the Ravages of Time

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Remyelination is the process by which new myelin sheaths are restored to demyelinated axons, and is a compelling example of how adult multipotent stem cells contribute to regeneration of the injured CNS . Understanding the processes underlying remyelination is crucial in the treatment for demyelinating diseases such as multiple sclerosis. There is now strong evidence that ageing is the major contributor to declining remyelination efficiency, and that this is largely due to a failure of stem cell differentiation. In this talk, Professor Franklin discusses recent studies on how ageing affects many aspects of CNS remyelination. Professor Robin Franklin is Professor of Stem Cell Medicine at the Wellcome Trust-MRC Cambridge Stem Cell Institute. He also serves as Director of the MS Society Cambridge Centre for Myelin Repair, and a Fellow of the Academy of Medical Sciences.

This talk is part of the SciSoc – Cambridge University Scientific Society series.

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