Microsystems for manipulating and measuring cells

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• Prof Joel Voldman, MIT
• Thursday 20 September 2007, 15:30-16:30
• IRC in Superconductivity Seminar room.

If you have a question about this talk, please contact spl37.

As cell biology moves to a more quantitative science, there has been an increasing need for new methods to study and manipulate individual cells and cell assemblies. In this talk I will describe our research in developing microtechnologies that allow us to measure and manipulate cells for both fundamental biology and biotechnology. Our research focuses on two technologies: dielectrophoresis, which acts as electrical “tweezers” for cells, and microfluidics, which we use to control the cell microenvironment. In this talk I will describe how we have combined these two technologies to create a variety of enabling systems. For example, we are using microfluidics and physical cell patterning to for modulating stem cell diffusible and contact-mediated signaling. We are also developing a number of technologies (electrical, optical, etc.) to allow for image-based sorting of cells, augmenting traditional microscopy with a sorting functionality. Finally, we have been developing electrical methods to separate cells that are ideally suited for novel screens.

This talk is part of the Nanoscience Centre Seminar Series series.

This talk is included in these lists:

• IRC in Superconductivity Seminar room
• All Talks (aka the CURE list)
• Cambridge Infectious Diseases
• Dobson Group - General Interest
• Nanoscience Centre Seminar Series
• School of Physical Sciences
• School of Technology

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