Whole-genome analysis of the structure and function of repressive chromatin

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• Dr Bas van Steensel, The Netherlands Cancer Institute
• Monday 11 December 2006, 13:30-14:30
• Shared facilities C209/210.

If you have a question about this talk, please contact Nicholas Luscombe.

Several types of chromatin protein complexes are thought to mediate repression of transcription, often by packaging of DNA into compact structures. We have begun a systematic genome-wide analysis of the genomic binding patterns of the most important repressive complexes: “classical” heterochromatin proteins, Polycomb Group proteins, histone H1, and nuclear lamina proteins. These genome-wide maps provide detailed and often surprising insights into the functions and interactions of these complexes.

This talk is part of the European Bioinformatics Institute series.

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