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Simulations of protein-lipid interactions in the mitochondria

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If you have a question about this talk, please contact Sven Friedemann.

Mitochondria are membrane-enclosed bodies in the cells of animals, plants and fungi that are responsible for generating most of the cell’s supply of ATP , the molecule used to transport energy around cells.

ATP synthase is the enzyme in the mitochondria that generates ATP via a molecular motor, the ATP synthase c-subunit, that lies in the mitochondrial membrane.

I will talk about simulations that I have performed of the ATP synthase c-subunit in the mitochondrial inner membrane, with particular attention to the interactions this protein makes with a particular lipid type – cardiolipin – which is characteristic of that membrane and known to be important in mitochondrial function.

This talk is part of the Darwin College Science Seminars series.

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