Proteins, Crystals and mechanisms

Add to your list(s) Download to your calendar using vCal

• Paul Elliott
• Thursday 07 March 2013, 13:10-14:00
• 1 Newnham Terrace, Darwin College.

If you have a question about this talk, please contact Sven Friedemann.

Structural biology provides a fundamental molecular understanding of biological processes. One of the most common ways to determine a protein structure is through its crystallisation and subsequent exposure to X-rays. Within this talk I shall highlight how one goes from a protein in solution to a crystal and finally to a three-dimensional structure. Along this way I shall point out some of the most common pitfalls that we face, almost seemingly on a daily basis. Finally, I will demonstrate with a specific example form our current research how structures provide a rational for enzyme mechanism and a more global implication in cellular signalling. This provides potential pharmacological targets for treating human diseases.

This talk is part of the Darwin College Science Seminars series.

This talk is included in these lists:

• 1 Newnham Terrace, Darwin College
• AUB_Cambridge Seminars
• All Talks (aka the CURE list)
• Cambridge Infectious Diseases
• Centre for Health Leadership and Enterprise
• Chris Davis' list
• Darwin College Research Talks
• Darwin College Science Seminars
• Darwin Lectures and Seminars
• Guy Emerson's list
• Interested Talks
• Neurons, Fake News, DNA and your iPhone: The Mathematics of Information
• custom

Note that ex-directory lists are not shown.