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LMB Seminar - Blueprints of Life: Understanding the Sex Chromosomes

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Sex chromosomes represent the only chromosome pair that differ between males and females, and as such are responsible for the myriad sexual dimorphisms observed in mammals. However, relative to the rest of the genome, their biology remains under explored. In this talk, I will describe how the sex chromosomes appeared during mammalian evolution, the mechanisms by which they regulate their most celebrated role in germline development, and their contribution to male-female differences in disease.

This talk is part of the MRC LMB Seminar Series series.

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