LMB Seminar - The DNA Quadruplex Helix

Add to your list(s) Download to your calendar using vCal

• Shankar Balasubramaniam, University of Cambridge
• Wednesday 19 March 2025, 10:00-11:00
• In person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom link https://mrc-lmb-cam-ac-uk.zoom.us/j/93702571246?pwd=I6zsi0w8N5XcKg2gu0bac58rcyTfba.1.

If you have a question about this talk, please contact Scientific Meetings Co-ordinator.

While DNA has been thought to exist primarily as a two-stranded double helix, there are alternative structures that can form. Particular G-rich sequences can fold into four-stranded structures called G-quadruplexes under physiological conditions. In this lecture, I will present our studies to explore the existence and function of G-quadruplexes structures in the DNA of cells and tissues in humans and in other species. The data suggests G-quadruplexes can play important roles in controlling transcription and cellular identity. Chemical biology approaches have been vital to help elucidate G-quadruplexes and provide insights into pathways for intervention that hold potential for therapeutics.

This talk is part of the MRC LMB Seminar Series series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• Biology
• CCC talks for website
• Cambridge Immunology
• Centre for Health Leadership and Enterprise
• In person in the Max Perutz Lecture Theatre (CB2 0QH) and via Zoom link https://mrc-lmb-cam-ac-uk.zoom.us/j/93702571246?pwd=I6zsi0w8N5XcKg2gu0bac58rcyTfba.1
• Liam
• Life Sciences
• Life Sciences
• ME Seminar
• MRC LMB Seminar Series
• Neurons, Fake News, DNA and your iPhone: The Mathematics of Information
• cri
• my_list
• other talks
• rc781

Note that ex-directory lists are not shown.