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The biology of CNS progenitor ageing

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  • UserProfessor Robin Franklin; Wellcome-MRC Cambridge Stem Cell institute, University of Cambridge, UK
  • ClockWednesday 24 March 2021, 15:00-16:00
  • HouseOnline via zoom.

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This talk will introduce the biology of the most abundant forms of stem/progenitor cell in the adult CNS - the OPC , its involvement in regeneration and adaptive learning, and its central role in why both these functions decline with aging. Published and unpublished data will be presented on how the age-state of the OPC is determined in very large part by extrinsic factors, primarily the mechanical features of the niche, and how the reprograming factor myc acts as a key regulator of age state.

This talk is part of the Babraham Seminar series.

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