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SUMMARY:The biology of CNS progenitor ageing - Professor Robin Franklin\; 
 Wellcome-MRC Cambridge Stem Cell institute\, University of Cambridge\, UK 
DTSTART:20210324T150000Z
DTEND:20210324T160000Z
UID:TALK151675@talks.cam.ac.uk
CONTACT:Bobbie Claxton
DESCRIPTION:This talk will introduce the biology of the most abundant form
 s of stem/progenitor cell in the adult CNS - the OPC\, its involvement in 
 regeneration and adaptive learning\, and its central role in why both thes
 e functions decline with aging. Published and unpublished data will be pre
 sented on how the age-state of the OPC is determined in very large part by
  extrinsic factors\, primarily the mechanical features of the niche\, and 
 how the reprograming factor myc acts as a key regulator of age state. 
LOCATION:Online via zoom
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