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VCAM1, brain ageing, and the 'vampire hypothesis'

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If you have a question about this talk, please contact Veronica Kane Dickson.

This week’s paper discusses the action of a key factor in brain ageing, VCAM1 , discovered to be relevant to what has been called the vampire hypothesis – effects of giving an old mouse young blood.

Please find the paper at https://www.nature.com/articles/s41591-019-0440-4

Yousef et al (2019) Nature Medicine. Aged blood impairs hippocampal neural precursor activity and activates microglia via brain endothelial cell VCAM1 .

This talk is part of the Dementia Journal Club series.

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