Mind the Gap: Nanotechnology for Molecular Sensing and Nanomedicine

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• Dr Jennifer Hare (AstraZeneca) and Dr Seti Kasera (Dept. Of Chemistry)
• Wednesday 13 April 2016, 18:30-20:00
• Postdoc Centre, 16 Mill Lane.

If you have a question about this talk, please contact Mark Dunning.

The clinical translation of anti-cancer nanomedicines from promising results in animal studies to a demonstration of therapeutic efficacy in patients is a significant challenge for the drug delivery field. Despite the heterogeneity observed in human cancers, there is limited understanding of the influence of tumour biology on nanomedicine efficacy. The speaker will discuss the assessment of nanomedicine accumulation, intra-tumoural distribution, and retention in xenograft and PDX tumours with different phenotypes. The ultimate aim is to aid in pre-selection efforts identifying the most suitable tumours to treat with nanomedicines. The second speaker will demonstrate how innovative developments in analytical chemistry using nanotechnology can simplify the testing procedures to detect biomarkers instantly in human urine for point-of-care diagnostics.

This talk is part of the "Life Sciences Masterclass" series.

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