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Probing gene control at the molecular stage

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  • UserProfessor Mark C. Leake, University of York World_link
  • ClockTuesday 23 February 2016, 16:00-17:00
  • HousePfizer LT.

If you have a question about this talk, please contact Alice Wood.

Genes can be switched on and off through the binding of proteins called transcription factors to specific regions of DNA . Here I will outline cutting-edge experiments and analyses using bespoke single-molecule fluorescence microscopy and theoretical biophysics approaches which enable us to monitor this process in individual living cells in their unique physical and chemical environment with molecular scale precision over a time scale faster than that set by the mobility of transcription factors themselves – in ‘real time’.

This talk is part of the Physical Chemistry Research Interest Group series.

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