A V HILL LECTURE - Oxygen sensing: from worms to people and genes to drugs

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• Professor Patrick Maxwell DPhil FRCP FMedSci, Regius Professor of Physic, School of Clinical Medicine
• Monday 25 January 2016, 18:00-19:00
• Bristol-Myers Squibb Lecture Theatre, Department of Chemistry.

If you have a question about this talk, please contact Beverley Larner.

Abstract: We have used biochemical methods and genetic approaches in a variety of organisms ranging from worms to man to investigate how cells sense oxygen, and what they do in response to changes in its availability. This has uncovered a highly conserved pathway which operates in all metazoans. It is important in development, physiology and disease – perhaps most notably in cancer. The underlying oxygen sensing mechanism can be activated by small molecules which are now being tested as therapies for anaemia and ischaemic conditions.

This talk is part of the Cambridge Philosophical Society series.

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