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Elastic instability and morphogenesis of the brain

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If you have a question about this talk, please contact Anna Walczyk.

The development of an adult organism from a single cell requires complex shapes to emerge from simple ones. In this talk I will discuss a growing body of evidence that the shapes of biological organs are often sculpted directly by mechanical forces rather than relying on chemical pre-patterning. In particular, I will discuss the elastically driven formation of cusped furrows at the boundary of any sufficiently compressed soft solid. I will then outline recent results showing these furrows underpin the morphogenesis of villi in the gut, and my own work linking them to sulci in the brain.

This talk is part of the Bioengineering Seminar Series series.

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