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Shaping and reshaping regulatory loops in Drosophila morphogen signaling.

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  • UserDr. Giorgos Pyrowolakis from BIOSS Centre for Biological Signalling Studies & Institute for Biology, University of Freiburg
  • ClockThursday 15 May 2014, 14:30-15:30
  • HousePart II Room, Department of Genetics.

If you have a question about this talk, please contact Caroline Newnham.

Host: Boris Adryan

Tight control of intercellular signaling by regulatory feedback mechanisms is key for proper growth and patterning of tissues and organs. I will present our recent efforts towards identifying feedback regulators in Drosophila BMP morphogen signaling and analyzing their impact in the establishment and maintenance of graded signaling. I will then focus on a prominent regulatory feedback loop of the pathway and present mechanisms by which tissue-specific cues might rewire regulatory feedback networks to impact on the shape of morphogen gradients and, ultimately, on the shape and function of organs.

This talk is part of the Genetics Seminar series.

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