Silencing RNAs are mobile and trigger DNA methylation in distant tissue

Add to your list(s) Download to your calendar using vCal

• Attila Molnar
• Friday 08 January 2010, 13:00-13:30
• Department of Plant Sciences, Large Lecture Theatre.

If you have a question about this talk, please contact ag586.

RNA silencing in plants has an effect at a distance – cells in which silencing is induced by small RNAs produce a signal that moves short distances through plasmodesmata and long distances through the phloem. The signal elicits nucleotide sequence-specific effects and so it is likely to have an RNA component as the specificity determinant. However, the mobile RNA has not been detected directly and its physical form is not known. Genetic evidence is ambiguous because there are multiple pathways of RNA silencing in plants with overlapping or interdependent functions. Using high throughput sequencing of small RNAs in analyses of grafted plants we demonstrated directly that 24 nt small RNAs are mobile. In addition we provide evidence that endogenous mobile small RNAs can cause changes in DNA methylation at a distance.

This talk is part of the Plant Sciences Research Seminars series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• Biology
• Biology
• CambPlants Hub
• Cambridge Global Food Security
• Department of Plant Sciences, Large Lecture Theatre
• Featured lists
• Life Sciences
• Life Sciences
• ME Seminar
• Plant Sciences Research Seminars
• my_list
• other talks

Note that ex-directory lists are not shown.