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Mechanism of neural differentiation

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If you have a question about this talk, please contact Caroline Newnham.

Host – Lara Busby

Using the remarkable spatial separation of the temporal events of neural differentiation along the embryonic vertebrate body axis we have discovered tissue interactions, signals and chromatin regulatory steps that direct this process https://sites.dundee.ac.uk/kate-storey/research/ . In this talk I will review this work and present recent studies linking FGF /ERK signalling to regulation of chromatin accessibility in human neuromesodermal progenitors, including unpublished phospho-proteomics data that identify chromatin-associated proteins targeted by ERK1 /2 and RSK .

This talk is part of the Genetics Seminar series.

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