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Visualising mRNA in a developing tissue

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If you have a question about this talk, please contact Dr Tamsin Samuels.

Grab some lunch from the Darwin servery and enjoy an interesting science talk and discussion over lunch. Looking forward to seeing you there.

Stem cells divide repeatedly, generating daughter cells which specialise to perform the different functions needed in a tissue. This process of specialisation involves dramatic changes in proteins in the cell, and the generation of these proteins is tightly regulated. Proteins are encoded for by genes in the DNA which can be switched on or off, but there are many additional layers of more precise control which act on the intermediate mRNA. Visualising mRNA molecules using microscopy during the process of differentiation allows us to understand these regulatory processes, and how they change dynamically in normal tissue development. Specifically, I use the model system of the fruit fly ovary to understand the regulation of germline stem cell specialisation to produce the egg.

This talk is part of the Darwin College Science Seminars series.

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