|COOKIES: By using this website you agree that we can place Google Analytics Cookies on your device for performance monitoring.|
RNA editing in plant organelles: Correlation between editing sites and protein three-dimensional structures
If you have a question about this talk, please contact Gos Micklem.
Ectopic seminar - N.B. in Biochemistry Department
In plant organelles, specific messenger RNAs (mRNAs) are subjected to conversion editing, a process that often converts the first or second nucleotide of a codon and hence of the encoded amino acid. No systematic patterns in converted sites were found on mRNAs, and the converted sites rarely encoded residues located at the active sites of proteins. The role and origin of RNA editing in plant organelles remain to be elucidated. Here we study the relationship between amino acid residues encoded by edited codons and the structural characteristics of these residues within proteins. We find that the residues encoded by edited codons are significantly biased toward involvement in helices and protein structural cores. The puzzling point of the finding is that the editing occurs on mRNA and protein 3D structures cannot play roles in the editing processes. We propose the cause of the observed correlation based on the evolution of land plants.
This talk is part of the Computational and Systems Biology series.
This talk is included in these lists:
Note that ex-directory lists are not shown.
Other lists6th Annual Cambridge Technology Ventures Conference - June 11th Royal Society Rosalind Franklin Seminar Series MRC/Hitachi Seminars
Other talksContact Line – Quo Vadis? Recurrence of a thymoma in a cat with metastatic spread Arguing about infinitesimals: a historiographic reflection on the origins/transmission of calculus Autumn Cactus & Succulent Show Evaluation of the tumour bed biopsy technique in canine and feline oncologic surgery 'Eastminster' - State-building in Asia in the aftermath of Empire