Linking Mammary Development and Breast Cancer

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• Professor Pamela Cowin, NYU School of Medicine
• Wednesday 14 June 2017, 16:00-17:00
• Lecture Theatre 2, Department of Veterinary Medicine.

If you have a question about this talk, please contact Fiona Roby.

Abstract: My group uses genetic approaches to study the intertwined roles of both Wnt and Hedgehog signaling in cell-fate decisions and amplification of stem and progenitor cell populations during embryonic and post-natal mammary development. We also investigate how these functions are linked to tumor onset and progression in adult mice. In an effort to identify further lineage markers with better prognostic utility for breast cancer subtypes we have begun to investigate a novel Adhesion-G-protein coupled receptor and a TGFbeta-binding protein, which identify early mammary stem/progenitors cells and specific luminal subpopulations respectively.

This talk is part of the Departmental Seminar Programme, Department of Veterinary Medicine series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• Cambridge Immunology
• Cambridge Infectious Disease
• Cambridge Infectious Diseases
• Departmental Seminar Programme, Department of Veterinary Medicine
• Lecture Theatre 2, Department of Veterinary Medicine
• Vet School Seminars

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