Abstract

There is a continuing need for improved signal-to-noise ratio in detection of magnetic resonance signals, since this can increase resolution both in MR imaging and in MR spectroscopy, and potentially allow earlier detection or diagnosis of potentially lethal tumours. Small, internal probes can increase SNR through a combination of closer coupling to the signal source and reduced sensitivity to body noise. However, microfabrication techniques are required to realise high-performance detectors at low cost and in clinically useful formats. This talk will provide an overview of the design issues and present examples of two recently demonstrated devices: a rigid needle-shaped detector designed for complete immersion in excised tissue and a flexible catheter-mounted detector capable of passing the biopsy channel of an endoscope and into the biliary duct system.