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Chromatin and Cell Cycle in Cell Fate Decision

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If you have a question about this talk, please contact Leonor Miller-Fleming.

In this masterclass, Dr. Clara Novo will: • discuss the presence of unusually permissive and hyper-transcribed chromatin in pluripotent embryonic stem cells • present evidence for an additional role for the open chromatin organisation • discuss how epigenetic regulation of satellite regions contribute to the genome integrity whilst providing a platform for cellular fate commitment

Our second speaker, Dr. Rodrigo Grandy will: • address the mechanisms that interlink cell cycle progression and cell cycle machinery to cell differentiation • present evidence that shed light onto whether the cell cycle plays any role during differentiation • present novel mechanisms of action for key elements of the cell cycle machinery during cellular differentiation.

This talk is part of the "Life Sciences Masterclass" series.

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