TODAY: Adrian Seminar - Corinne Houart "Modulation of embryonic signalling activities controls forebrain size and complexity"

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• Corinne Houart, King's College London
• Monday 06 November 2017, 16:30-18:00
• The Hodgkin Huxley Seminar Room, Department of Physiology Development and Neuroscience.

If you have a question about this talk, please contact Lyn Dakin.

Abstract: The diversity in vertebrate brain size, shape and complexity underpins the vast spectrum of behaviours, social and cognitive abilities found across species. During development, variations in temporal and spatial regulation of neurogenesis have been shown to play an important role in creating this diversity. Here, we present evidence unveiling another mechanism involved in imposing substantial change in brain size and ultimately function. We performed a comparative functional study between zebrafish and mouse, focused on early signalling events shaping the brain territories in late gastrula/early neurula. We will share our findings indicating that simple temporal changes in signalling induction is able to modify both size and function of the vertebrate forebrain.

This talk is part of the Adrian Seminars in Neuroscience series.

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