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"Function and modulation of sensory TRP channels"

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“Transient receptor potential (TRP) channels form a superfamily of cation channels involved in a wide variety of physiological and pathophysiological processes. In particular, several mammalian TRP channels are expressed in sensory neurons, where they act as molecular sensors of thermal and chemical cues. Here, an overview will be provided of recent insights into the molecular and cellular regulation of somatosensory TRP channels, and how this impacts on thermosensation. Finally, the involvement of sensory TRP channels in pathophysiological processes will be illustrated, and the potential of these channels as novel drug targets will be discussed.”

This talk is part of the Adrian Seminars in Neuroscience series.

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