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Motion sensitive circuits in the retina

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Inferring the direction of image motion is a fundamental component of visual computation, and essential for visually guided behavior. Even at the front of the visual stream, in the retina, a number of parallel circuits extract information about motion. I perform cell-type-specific experiments to understand the development and function of direction-selective circuit in mouse retina. My talk will have two parts. First I show how and when spatially asymmetric synaptic connectivity, which is a key circuit module of direction-selective circuit, is established during development. Second I discuss the computational logic of direction selectivity, based on our recent study in which we recorded the concerted activity of the circuit elements of single direction-selective cells at subcellular resolution while these circuit elements were computing a specific task.

This talk is part of the MRC LMB Neurobiology Seminars series.

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