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Single Cell Seminars (September)

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If you have a question about this talk, please contact Lia Chappell.

Please come along to the monthly campus Single Cell Seminar series. All are welcome, include colleagues from Cambridge (though email me so we can book them in as a visitor with security)

Speaker 1: Qianxin Wu (Cell Ops R&D) ”Targeted single cell transcripts profiling with combinatorial indexing (sci-rna-seq)”

Speaker 2: Valentine Svensson (Teichmann group) ”Bioinformatics Journal Club: ZINB -WaVE”

Qianxin will be giving an update on progress on her work with the sci-rna-seq protocol, which can process thousands of fixed cells in parallel. The bioRxiv manuscript was discussed in a previous single cell seminar, and the protocol has recently been published by the Shendure lab in Science (

Valentine will be presenting a journal club on the ZINB -WaVE manuscript posted on bioRxiv ( The authors claim that ZINB -WaVE provides a “general and flexible method for signal extraction from single-cell RNA -seq data”, that can handle zero inflation (dropouts), over-dispersion, and the count nature of the data. Valentine will explain some of the underlying concepts, but do look at the paper if you can.

This talk is part of the Single Cell seminars at the Wellcome Genome Campus series.

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