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University of Cambridge > Talks.cam > Plant Sciences Research Seminars > Riddle of the Sphinx: Sphingolipid glycosylation - a possible role in plant immunity?
Riddle of the Sphinx: Sphingolipid glycosylation - a possible role in plant immunity?Add to your list(s) Download to your calendar using vCal
If you have a question about this talk, please contact . The Arabidopsis Golgi-localised protein, GONST1 , is a GDP -Mannose transporter that was thought to provide precursors for the synthesis of cell wall polysaccharides such as glucomannan. Using liposome assays, we showed that GONST1 can transport all four plant GDP -linked monosaccharide sugars: GDP -Man, GDP -Glc, GDP -L-Gal and GDP -Fuc. However, gonst1 mutants have no detectable alterations in cell wall polysaccharides synthesized from these precursors. In contrast, we showed that glycosylinositolphosphoceramide (GIPC) sphingolipid headgroups contain mannose and that these decorations are decreased in gonst1 GIP Cs. gonst1 plants have a dwarfed phenotype, and a constitutive hypersensitive response with elevated salicylic acid. This suggests an unexpected role for GIPC sugar decorations in sphingolipid function and plant defence signalling. This talk is part of the Plant Sciences Research Seminars series. This talk is included in these lists:
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