University of Cambridge > Talks.cam > Cambridge Neuroscience Seminars > New Insights into the Mechanisms and Selectivity of Protein Degradation by the Proteasome Pathway

New Insights into the Mechanisms and Selectivity of Protein Degradation by the Proteasome Pathway

Add to your list(s) Download to your calendar using vCal

If you have a question about this talk, please contact Dr Dervila Glynn.

Fred Goldberg is a Professor of Cell Biology at Harvard Medical School and is visiting Cambridge as a guest of St. John’s College.

Fred has been fascinated by protein degradation pathways since his first days as a professor at Harvard in the 1970’s. The general opinion at the time was that the cell’s garbage collection was mostly done by the lysosome. Always pushing at the frontiers of cell biology, Fred discovered the proteasome and then it’s famous inhibitor MG-­‐132. With careful chemical manipulations his group was able to generate the related compound bortezomib that is now a billion dollar drug used for the treatment of a haematological cancer called myeloma.

This talk is part of the Cambridge Neuroscience Seminars series.

Tell a friend about this talk:

This talk is included in these lists:

Note that ex-directory lists are not shown.

 

© 2006-2019 Talks.cam, University of Cambridge. Contact Us | Help and Documentation | Privacy and Publicity