Determining the direction of communication between the hippocampus and neocortex with layer-specific fMRI.

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• Oliver Warrington (UCL)
• Monday 21 October 2024, 12:30-13:30
• MRC-CBU, 15 Chaucer Road, Cambridge.

If you have a question about this talk, please contact Dace Apšvalka.

Speaker: Oliver Warrington, University College London (UCL), visiting in person.

Title: Determining the direction of communication between the hippocampus and neocortex with layer-specific fMRI.

Abstract: Interactions between the hippocampus and neocortex are essential for many cognitive functions, including my main interests – perception and memory. Therefore, a major aim of cognitive neuroscience is to characterise the nature of these interactions, particularly their directionality. Until recently, this was not feasible with fMRI and remained the domain of invasive animal experiments. Now, however, 7T fMRI offers the spatial resolution for non-invasive, layer-specific measures of neural activity in humans, allowing us to infer the direction of communication through our knowledge of the anatomical connections between the hippocampal subfields and neocortical layers. In this talk, I will give an overview of my PhD research using this method to investigate neural mechanisms underlying the effect of prior knowledge on perception.

Bio: Oliver Warrington is a PhD student with Peter Kok and Eleanor Maguire at the Functional Imaging Laboratory, UCL . His work investigates mesoscale neural mechanisms using 7T layer-specific fMRI in an attempt to bridge the gap between his biochemistry background and his fascination with perception and memory.

Venue: MRC CBU West Wing Seminar Room and Zoom https://us02web.zoom.us/j/82385113580?pwd=RmxIUmphQW9Ud1JBby9nTDQzR0NRdz09

This talk is part of the CBU Monday Methods Meeting series.

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