Mimicking cell-surface machinery with bespoke DNA nanostructures

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• Roger Rubio Sanchez (University of Cambridge)
• Thursday 04 May 2023, 11:30-12:30
• Open Plan Area, Institute for Energy and Environmental Flows, Madingley Rise CB3 0EZ.

If you have a question about this talk, please contact Catherine Pearson.

Biological membranes must tightly regulate the lateral distribution of inclusions to facilitate the key functionalities they host, ranging from signal transduction to molecular trafficking and cellular motion. Bottom-up synthetic biology aims to replicate behaviours usually observed in living matter in cell-like objects called “artificial cells”, so to deepen our understanding of biological processes as well as to unlock promised technological applications in biomedicine, biosynthesis, and bioremediation. Exploiting the tools of self-assembly, chemical nanotechnology, and membrane biophysics, my research uses DNA molecules to build two- and three-dimensional nano-scaled architectures that can replicate the structure and function of membrane proteins, allowing us to engineer functionality in the lipid membrane of artificial cells.

This talk is part of the Institute for Energy and Environmental Flows (IEEF) series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• Cambridge Energy Seminars
• Department of Earth Sciences seminars
• Institute for Energy and Environmental Flows (IEEF)
• NanoDTC Energy Materials Talks
• Open Plan Area, Institute for Energy and Environmental Flows, Madingley Rise CB3 0EZ
• history
• ps635

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