University of Cambridge > > Chemical Engineering and Biotechnology Departmental Seminars > In Focus seminars at CEB: Eleni Stavrinidou Linköping University

In Focus seminars at CEB: Eleni Stavrinidou Linköping University

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In-vivo polymerization of conjugated oligomers for self-organized electronics in plants and animals

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Leveraging the biocatalytic machinery of living organisms for fabricating functional bioelectronic interfaces in-vivo not only enables seamless integration of microdevices into the tissue but also a greener solution for advanced microfabrication. Previously we have demonstrated that plants can polymerize conjugated oligomers in-vivo forming conductors within their structure. We showed that the polymerization is enzymatically catalyzed by endogenous peroxidases and we developed a series of conjugated oligomers that can be enzymatically polymerized in physiological conditions. The conjugated polymers integrate within the plant cell wall structure adding electronic functionality into the plant that is then explored for energy storage. Recently we demonstrated intact plants with electronic roots that continue to grow and develop enabling plant-biohybrid systems that maintain fully their biological processes. Furthermore, we have extended this concept into an animal model system. We demonstrated that Hydra, an invertebrate animal, can polymerize intracellularly conjugated oligomers in cells that expresses peroxidase activity. The conjugated polymer forms electronically conducting and electrochemically active domains in the µm range integrated within the hydra tissue. Our work paves the way for self-organized electronics in plant and animal tissue for modulating biological functions and in-vivo bio-fabrication of hybrid functional materials and devices.

This talk will be delivered in a hybrid format. A limited number of tickets are available for University of Cambridge members to join in person, in the Weston Lecture Theatre at CEB - please register with your University of Cambridge email address.

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This talk is part of the Chemical Engineering and Biotechnology Departmental Seminars series.

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