University of Cambridge > Talks.cam > MRC Mitochondrial Biology Unit Seminars > Mito-nuclear interactions and mitochondrial replacement therapy: an evolutionary perspective

Mito-nuclear interactions and mitochondrial replacement therapy: an evolutionary perspective

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It has been suggested that mito-nuclear interactions may potentially be harmful to individuals conceived through mitochondrial replacemet therapy (MRT). In my talk I will consider this problem from an evolutionary perspective. I will argue that deleterious mito-nuclear interactions, though they may exist, are unlikely to be more common amongst individuals born to MRT than normal conception. I will present evidence from model organsisms which supports this conjecture.

This talk is part of the MRC Mitochondrial Biology Unit Seminars series.

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