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DNA-repairing proteins: View of a structural biologist

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What do you do when your DNA is broken? Call for repair. The cell needs a healthy DNA so to faithfully read instruction carried in our genes. Our DNA daily undergoes physical damage as we interact with the environment. The cell has evolved a fascinating system made up of proteins that signal and repair broken DNA . My work focused on the two protein enzymes called ATM and ATR . I was hoping to get more functional insights by studying the molecular architecture of ATM /R using the electron microscope. In my talk I would like to share with you my latest findings.

This talk is part of the Darwin College Science Seminars series.

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