Pulse and Surge Generation by the GnRH Neuronal Network for Fertility

Add to your list(s) Download to your calendar using vCal

• Professor Allan Herbision
• Tuesday 04 July 2017, 16:00-17:00
• Hodgkin-Huxley Lecture Room, Department of Physiology Development and Neuroscience.

If you have a question about this talk, please contact William Colledge.

The gonadotropin-releasing hormone (GnRH) neurons have an unusual neuronal phenotype in that they migrate from the nose into the brain during embryogenesis to ultimately control reproductive hormone secretion and fertility in all vertebrates. The GnRH neurons embed themselves into a neuronal network that enables them to generate two different types of episodic activity that drive “pulse” and “surge” patterns of hormone secretion. Studies in genetically manipulated mice using viral tract-tracing, electrophysiology, and a range of in vivo optogenetic and chemogenetic approaches are beginning to shed light on the key neuronal circuitries responsible for driving these different modes of episodic activity.

This talk is part of the whc23's list series.

This talk is included in these lists:

• Hodgkin-Huxley Lecture Room, Department of Physiology Development and Neuroscience

Note that ex-directory lists are not shown.