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Inducing and Breaking Tolerogenic Dendritic Cell Function

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  • UserMeeting chairs: : Dr Leonie Taams, Senior Lecturer in Immunology, King's College London Centre for Molecular and Cellular Biology of Inflammation and Dr Catharien Hilkens, Reader in Immunotherapy, Newcastle University , UK
  • ClockThursday 05 July 2012, 09:00-17:00
  • HouseThe Penridge Suite, 470 Bowes Road, London N11 1NL.

If you have a question about this talk, please contact Dr Shara Cohen.

Professional antigen-presenting cells (APC) such as dendritic cells (DC) and macrophages play a critical role in the initiation and maintenance of a T cell-mediated immune response. APC are essential for T cell priming, differentiation and activation in lymphoid tissue and at sites of inflammation. Understanding the molecular mechanisms via which APC function can be controlled may give novel insights into how T cell mediated immunity may be induced or blocked. This meeting will highlight current research aimed at inducing dendritic cells with tolerogenic function in order to treat inflammatory disease (e.g. rheumatoid arthritis) as well as work aimed at boosting the immunostimulatory function of dendritic cells in the context of cancer. The meeting will also highlight recent progress on the suppressive effects of CD4 + regulatory T cells on APC function, and how these can be overcome.

This event has CPD accreditation and will have a discussion panel session.

This talk is part of the Euroscicon series.

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