Clozapine, mortality and other lies

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• Dr Emilio Fernandez-Egea
• Thursday 07 November 2024, 12:30-13:30
• Online via zoom.

If you have a question about this talk, please contact Oliver Knight.

While clozapine has risks, relative risk of fatality is overestimated. The UK pharmacovigilance programme is efficient, but comparisons with other drugs can mislead because of reporting variations. Clozapine actually lowers mortality, partly by reducing schizophrenia-related suicides, but preventable deaths still occur. Clozapine should be used earlier and more widely, but there should be better monitoring and better management of toxicity. In this talk, we will cover the evidence about mortality in schizophrenia, the effect of clozapine initiation in mortality and the next steps we should be taking to reduce the mortality gap in people with SMI .

This talk is part of the Department of Psychiatry & CPFT Thursday Lunchtime Seminar Series series.

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