NMR, drugs and targets

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• Dr Bill Broadhurst & Dr Daniel Nietlispach
• Wednesday 31 March 2021, 15:30-16:30
• https://youtu.be/VTvBaCdy_fE.

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Join us on our YouTube channel to watch this talk live and take part in a Q&A session with the speakers: https://youtu.be/VTvBaCdy_fE

Cheap technologies for reading and tinkering with bacterial genome sequences have opened up new possibilities in the arms race against multi-drug-resistant diseases. This approach could breathe new life into old medicines.

Every cell in our body is surrounded by a fatty membrane that is loaded with many proteins. Some of these proteins act as sensors that link the cell interior with the outside world of the cell. Through a better understanding of how these proteins work we will find new approaches that cure untreatable diseases.

The structural biology technique nuclear magnetic resonance (NMR) spectroscopy is being applied to both of these fields of research in order to reveal new details about the secret lives of proteins.

This talk will be given by Bill Broadhurst and Daniel Nietlispach from the Department of Biochemistry and will be followed by a Q&A session.

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Bill Broadhurst, a Lecturer in the Department of Biochemistry, uses NMR spectroscopy to study the structure and flexibility of biological macromolecules. Daniel Nietlispach, a Reader in the Department of Biochemistry, uses NMR spectroscopy to investigate functional aspects of membrane proteins.

This talk is part of the Department of Biochemistry, Cambridge Science Festival Talks (2021) series.

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