LMB Seminar Series: Extracting function from structure: Lessons from the adult fly connectome

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• Gerry Rubin, Vice President, HHMI, and Executive Director, Janelia Research Campus
• Friday 03 April 2020, 11:00-12:00
• Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

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A complete wiring diagram, or connectome, of the Drosophila central nervous system will soon be available, providing the first glimpse of synaptic-level connectivity of the brain of an animal with sophisticated behavior. I will briefly review the series of technical advances that made this possible, and what obstacles remain to be overcome before the connectomes of larger animals can be pursued. Then I will discuss the challenge of how to use the wiring diagram—together with light microscopy, genetically targeted physiology and perturbation during behavior—to understand the neural basis of associative learning, perception, sleep, navigation and more.

This talk is part of the MRC LMB Seminar Series series.

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