Towards XNA molecularbiology: reinventing biology one protein at a time

Add to your list(s) Download to your calendar using vCal

• Dr Vitor Pinheiro
• Tuesday 03 March 2020, 13:00-14:00
• Department of Biochemistry, Sanger Building, Thomas Lecture Theatre.

If you have a question about this talk, please contact Florian Hollfelder.

Life on Earth, despite its diversity, is restricted to a narrow range of chemical reactions, structures and materials. Although all life relies on DNA and RNA for their chemical information storage, it is now clear that many other synthetic genetic materials (or XNAs) are possible and could functionally substitute DNA . Nevertheless, DNA doesn’t function in isolation,it is supported by a range of DNA binding proteins and nucleic acid processing enzymes – none of which are available for XNA . With a view towards creating aviable XNA episome in vivo, we have focused on the systematic development of XNA processing enzymes, primarily by directed evolution. My talk will present some of this trajectory as well as some of the tools and platforms that we have developed but that have wider applications.

This talk is part of the Seminars at the Department of Biochemistry series.

This talk is included in these lists:

• Cambridge Infectious Diseases
• Department of Biochemistry, Sanger Building, Thomas Lecture Theatre
• Engineering Biology Interdisciplinary Research Centre
• PMRFPS's
• Seminars at the Department of Biochemistry
• biochem seminars
• ndk22's list
• rc781
• se393's list

Note that ex-directory lists are not shown.