DEVELOPMENT OF BIOMATERIALS AND CELL THERAPIES FOR BONE REGENERATION

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• José Miguel Campos DVM MRCVS, Veterinary Clinics, Abel Salazar Institute of Biomedical Sciences (ICBAS), University of Porto (UP), Porto, PORTUGAL
• Wednesday 24 January 2018, 16:00-17:00
• Lecture Theatre 2, Department of Veterinary Medicine.

If you have a question about this talk, please contact Fiona Roby.

“Autologous bone graft remains the ‘gold standard’ grafting substrate available in bone fusions for small gaps and in critical defects. However, significant morbidity is associated with the harvesting of autologous bone graft and alternative bone graft substitutes have been developed. In the present pre-clinical study, a synthetic bone graft called Bonelike® (BL®) was tested. BL® is a glass-reinforced hydroxyapatite composite with osteoinductive and osteoconductive proprieties. These proprieties of BL® have been confirmed in experimental models of bone regeneration in sheep and recently its application in orthopedic and stomatological pathologies is being tested in small animal (SA) clinics. In the present study, we have been also studying the mesenchymal stem cells (MSCs) isolated from the dental pulp (DPSCs) which were characterized in vitro and expanded for in vivo application. The osteogenic potential of DPS Cs associated to a modified hydroxyapatite bone substitute was further evaluated in vivo in a monocortical ovine model.”

This talk is part of the Departmental Seminar Programme, Department of Veterinary Medicine series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• Cambridge Immunology
• Cambridge Infectious Disease
• Cambridge Infectious Diseases
• Departmental Seminar Programme, Department of Veterinary Medicine
• Lecture Theatre 2, Department of Veterinary Medicine
• Vet School Seminars

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