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Novel Biomaterials and Technology for use in Regenerative Medicine/Tissue Engineering

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Keywords: stem cell, tissue engineering, periodontal ligament, in situ models, Articular cartilage; osteoarthritis; tissue engineering; regenerative medicine; 3-dimensional culture, Bone graft, biomaterial, surface structure, osteoinduction, lung, epithe

This meeting brings together the principles of engineering and life sciences in tissue development and regenerative medicine to discuss scientific research and developments of clinical applications from leading experts in the field. The newest research and developing technology will be discussed in an informal setting with plenty of networking opportunities. This event has CPD accreditation.

This event is part of the Tissue Engineering Congress 2014 – http://tissueengineeringcongress2014.com/

To see the full agenda please go to http://lifescienceevents.com/wp-content/uploads/4thJuneRegen2014.pdf

Meeting Chair: Dr Xuebin Yang, Head of Tissue Engineering Research, University of Leeds, UK

Who Should Attend Biotech and Pharma Industry: CEOs, Chief Scientists, Group Heads, Senior and Junior Scientists, Research Managers Academic and Research Institutes: Group and Lab Heads, Postdoctoral Scientists and Research Student

The deadline for abstract submissions for oral presentation is March 10th 2014. Abstracts for poster presentation only can be submitted up to two weeks before the event. You can download the instructions for authors at www.euroscicon.com/AbstractsForOralAndPosterPresentation.pdf

Talks include

Functional biomaterials for skeletal tissue engineering Dr Xuebin Yang, Head of Tissue Engineering Research, University of Leeds, UK Biomaterial is one of the key elements required for tissue engineering. There has been a push in the field of tissue engineering to develop unique biomaterials, or tissue specific scaffolds. Since tissue engineering is a dynamic process, the ideal scaffold should be biocompatible, biodegradable, bioactive and capable of supporting cell attachment, adhesion, proliferation, as well as controlling differentiation, production of extracellular matrix. This will allow tissue to regenerate, remodel and function in a physiological manner. This talk will demonstrate the use of different 3D scaffolds for skeletal tissue engineering both in vitro and in vivo, and discuss the functional elements for the design and fabrication of novel biomaterial scaffolds.

Optimization of a tissue engineered bilayered skin subtitute: striving ofr a positive clinical impact. Dr François A. Auger, Director of LOEX , Full university professor, Department of Surgery, Université Laval, Québec, QC, Canada For the treatment of deep or recurring skin wounds, the availability of a skin substitute that includes both dermal and epidermal layers is clinically desirable. The presence of the dermal layer, in addition to reinforcing the fragile cultured epidermis, adds a number of physiological functions to the skin substitute. Clinical data indicates it helps wound healing and reduces scarring. The bilayered skin substitute made at the LOEX is showing much promise for the treatment of burn patients and lower extremity venous and mixed chronic ulcers. A new accelerated production method for this skin substitute is being developed.

Direct cytotoxicity evaluation of biomaterials by micro/nano calorimetry: a new method for materials biocompatibility evaluation Dr Ali Doostmohammadi, Head of Materials Department, Shahrekord University, Iran The evaluation of biocompatibility is one of the most important assessments to be performed prior to clinical use of biomaterials. There is a need for a convenient method for screening of biocompatibility and cytotoxicity (as a criterion of biocompatibility), a method that can directly evaluate cell growth as well as cell adhesion to biomaterials surfaces. Isothermal micro-nano calorimetry (IMNC) is capable of measuring the heat production or consumption rate in the microW range with a calorimeter operating at nearly a constant temperature. Therefore, this technique allows direct and continuous monitoring of the metabolic activity of living cells.

A Novel Control Release Platform of Porous PLGA /Gelatin Composite for Fast Induction of Mouse Embryonic Stem Cell Differentiation Professor Gou-Jen Wang, National Chung-Hsing University, Taiwan A specifically designed scaffold can enhance the division, proliferation, and differentiation of embryonic stem cell. In this study, various porous PLGA /Gelatin scaffolds coated with mixed solution of gelatin and vascular endothelial cell conditioned medium (ECCM) on the scaffold and pore inner surfaces are proposed. The PLGA /gelatin composited scaffold serves as a control release platform to induce the differentiation of mouse embryonic stem cell into endothelial-like cell. Without any additional growth factor, the starting differentiation time point of mouse embryonic stem cell cultured on the proposed control release scaffolds can be reduced to 1/2 of that of the conventional approaches.

Additional Speakers include Professor Masaru Tanaka, Department of Biochemical Engineering,Yamagata University, Japan Dr Steve Bloor, Videregen, UK Associate Professor Fariba Dehghan, Director of bioengineering and Postgraduate coursework, The University of Sydney, Australia Speaker to be confirmed, Bose ElectoForce, Germany Dr Florelle Gindraux, Université de Franche Comté, France

This talk is part of the euroscicon series.

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