|COOKIES: By using this website you agree that we can place Google Analytics Cookies on your device for performance monitoring.|
Hepcidin, immunity and global health
If you have a question about this talk, please contact Sue Griffin.
Host: Adrian Kelly (email@example.com)
Iron lies at the center of a battle for nutritional resource between higher organisms and their microbial pathogens. The iron status of the human host affects the pathogenicity of numerous infections including malaria, HIV -1, and tuberculosis.
Hepcidin, an antimicrobial-like peptide hormone, has emerged as the master regulator of iron metabolism. Hepcidin controls the absorption of dietary iron and the distribution of iron among cell types in the body, and its synthesis is regulated by both iron and innate immunity.
We describe how hepcidin integrates signals from diverse physiological inputs, forming a key molecular link between iron trafficking and response to infection. Manipulation of hepcidin constitutes a new method for controlling immunity.
This talk is part of the Immunology in Pathology series.
This talk is included in these lists:
Note that ex-directory lists are not shown.
Other listsAll CMS Events The George Macaulay Trevelyan Lectures 2012 Centre for Family Research
Other talksA Direct Coupling Coherent Quantum Observer Developing Sustainable Architecture Histopathology 2014: Advances in research and techniques Regulated cell death: from apoptosis to necroptosis The 2015 TB Summit Title: TBA (Prof. Thomas F. Krauss FRSE, University of York)