"Spatio-temporal regulation of antigen presentation and cell migration"

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• Dr Ana-Maria Lennon-Duménil, Institute Curie, Paris. Hosted by Marion Espeli
• Friday 18 May 2012, 13:00-14:00
• Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research.

If you have a question about this talk, please contact Catie Heathfield.

Ana-Maria Lennon-Dumenil is a young group leader at the Institut Curie in Paris and is interested in the cell biology of antigen-presenting cells (see recent publications below).

Ana-Maria will have some time for discussion after her talk. If you are interested in meeting her could you please send an email to Marion Espeli (me301@cam.ac.uk)?

Selected publications: Polarized secretion of lysosomes at the B cell synapse couples antigen extraction to processing and presentation. Yuseff MI, Reversat A, Lankar D, Diaz J, Fanget I, Pierobon P, Randrian V, Larochette N, Vascotto F, Desdouets C, Jauffred B, Bellaiche Y, Gasman S, Darchen F, Desnos C, Lennon-Duménil AM. Immunity. 2011 Sep 23;35(3):361-74. Epub 2011 Aug 4.

Regulation of dendritic cell migration by CD74 , the MHC class II-associated invariant chain. Faure-André G, Vargas P, Yuseff MI, Heuzé M, Diaz J, Lankar D, Steri V, Manry J, Hugues S, Vascotto F, Boulanger J, Raposo G, Bono MR, Rosemblatt M, Piel M, Lennon-Duménil AM. Science. 2008 Dec 12;322(5908):1705-10.

The actin-based motor protein myosin II regulates MHC class II trafficking and BCR -driven antigen presentation. Vascotto F, Lankar D, Faure-André G, Vargas P, Diaz J, Le Roux D, Yuseff MI, Sibarita JB, Boes M, Raposo G, Mougneau E, Glaichenhaus N, Bonnerot C, Manoury B, Lennon-Duménil AM. J Cell Biol. 2007 Mar 26;176(7):1007-19.

Syk-dependent actin dynamics regulate endocytic trafficking and processing of antigens internalized through the B-cell receptor. Le Roux D, Lankar D, Yuseff MI, Vascotto F, Yokozeki T, Faure-André G, Mougneau E, Glaichenhaus N, Manoury B, Bonnerot C, Lennon-Duménil AM. Mol Biol Cell. 2007 Sep;18(9):3451-62. Epub 2007 Jun 27.

This talk is part of the Immunology and Medicine Seminars series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• Cambridge Immunology
• Cambridge Infectious Disease
• Cambridge Infectious Diseases
• Immunology and Medicine Seminars
• LMB
• Liam
• Sackler Lecture Theatre (Level 7), Cambridge Institute for Medical Research

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