Ubiquitin flips the anaphase switch

Add to your list(s) Download to your calendar using vCal

• David Morgan, UCSF
• Friday 13 April 2012, 16:15-18:00
• Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol.

If you have a question about this talk, please contact Scientific Meetings Co-ordinator.

Chromosome segregation in anaphase of mitosis is triggered by a giant ubiquitin ligase called the Anaphase-Promoting Complex or cyclosome (APC). We are studying the biochemical mechanisms by which the APC binds its substrates and modifies them processively with polyubiquitin chains. Our recent work has focused on the mechanisms that inhibit APC activity when defects in the mitotic spindle delay the onset of anaphase.

This talk is part of the MRC LMB Seminar Series series.

This talk is included in these lists:

• All Talks (aka the CURE list)
• Biology
• CCC talks for website
• Cambridge Immunology
• Centre for Health Leadership and Enterprise
• Liam
• Life Sciences
• Life Sciences
• ME Seminar
• MRC LMB Seminar Series
• Max Perutz Lecture Theatre, Medical Research Council (MRC) (MRC Laboratory of Molecular Biol
• Neurons, Fake News, DNA and your iPhone: The Mathematics of Information
• cri
• my_list
• other talks
• rc781

Note that ex-directory lists are not shown.