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Sequential optimal dose finding

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If you have a question about this talk, please contact Mustapha Amrani.

Design and Analysis of Experiments

We consider a typical phase I/II trial where the objective is to find the MTD as well as efficient estimation of the underlying parameters of the model. First, we discuss various design strategies. We then provide a group sequential strategy for updating the optimal design distribution in a group-wise manner. The sequential optimal design converges to the true optimal design.

This talk is part of the Isaac Newton Institute Seminar Series series.

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