University of Cambridge > Talks.cam > Departmental Seminar Programme, Department of Veterinary Medicine > Insights into the pathogenicity of Haemophilus parasuis; implications in diagnosis and control

Insights into the pathogenicity of Haemophilus parasuis; implications in diagnosis and control

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Haemophilus parasuis is an early colonizer of piglets and the etiological agent of Glasser’s disease. Many factors influence the balance between colonization and pathology and only a fraction of farms actually develops clinical disease. These factors include management procedures, presence of other pathogens or degree of virulence of the strains of H. parasuis in the farm. H. parasuis strains are very heterogeneous and, for diagnosis and control, it is important to differentiate between non-virulent (colonizers) and virulent strains. Our laboratory has found genetic differences that correlate with differences in functional assays. We have identified a family of trimeric autotransporters with potential use in diagnosis and vaccination against disease by H. parasuis.

This talk is part of the Departmental Seminar Programme, Department of Veterinary Medicine series.

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