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Structural biology of bacterial secretion systems

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The Waksman lab has recently solved the structure of very large complexes involved in forming the secretion nanomachines responsible for transport of transforming proteins and adhesive polymers through the double membrane of gram-negative bacteria. These complexes shed unprecedented light onto the mechanisms these secretion systems employ to secrete macromolecular virulence factors important in pathogenesis

This talk is part of the MRC LMB Seminar Series series.

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